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Publication 56: Synthesis of a Precursor to Sacubitril Using Enabling Technologies

Ley's group report an improved flow-through diastereoselective Reformatsky-type carboethoxyallylation in the synthesis of a key intermediate in the preparation of sacubitril  ...more

Application Note 30Copper Catalysed N-Arylation
Diaryliodonium salts are effective alkylating agents of anilines under flow-through conditions in a copper coil reactor ... more

Application Note 29: 2-Step Conversion of Acetophenones into Pyrazoles

Scientists at Galchimia report a general 2 step process for the preparation of pyrazoles starting from acetophenones that can be run as a continuous flow process ... more

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