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Poster 5: Iodination and Protection of Heterocycles in Flow
Workers at the University of Orleans report a 2 stage, continuous flow-through approach for the iodination of indoles and related heterocycles followed by their subsequent BOC protection.
Yields and purities reported contrast favourably with those obtained under batch conditions, however much shorter reaction times were achievable in flow.
Indoles and related heterocycles are important chemotypes of considerable interest in drug discovery.
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Poster 4: Control of Mixing and Temperature using Static Mixers
Meso-scale Glass Static Mixers can be used as scaleable flow reactors for rapid chemistries. This poster was first presented at the Uniqsis Flow Chemistry Symposium, Cambridge, 2009.
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Poster 3 (Sygnature): Preparation of Azides under Segmented Flow Conditions
Azides can be prepared by nucleophilic displacement of halides under segmented flow-through conditions in a flow reactor. This poster was first presented at the Uniqsis Flow Chemistry Symposium, Cambridge, 2009.
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Poster 2: FlowSyn: An Integrated Bench-top Continuous Flow Reactor
Please download the poster which was presented at the Pittcon exhibition/conference 2008 in New Orleans.
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Poster 1: Flow Synthesis: Reaction Optimisation and Scale-up in Meso-reactors
Please download the poster which was presented at the Pittcon exhibition/conference 2008 in New Orleans.
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