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What is flow chemistry?

Flow Chemistry is a technique which can be used for reaction optimization, synthesis and scale up of chemical reactions. Reactions take place in microchannels ranging in size from a few microns up to 1mm inner diameter.

Due to the size of the reactors excellent heat and mass transfer is achieved which leads to:

• Higher reaction yields vs. traditional chemistry systems
• Better selectivity
• Scalability is achieved by simply pumping continuously the reagents
• Reactions performed in such a small volume are intrinsically safer than traditional synthesis methods, especially when handling hazardous reagents and highly exothermic reactions, e.g. nitrations, oxidations, etc.
• Allows the chemist to optimize reaction conditions and use them to produce the required amount without a need to re-optimise.

Mixing occurs in a T-shaped mixer which allows diffusion across a short distance. This results in rapid and controlled mixing. Laminar flow is observed which leads to excellent reproducibility compared with turbulent flow.