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FlowSyn heats up to 260ºC
02/06/2008
Raising the reaction temperature achievable with the FlowSyn™ Continuous Flow Reactor has considerably widened the scope of reactions that can be performed.
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Latest press release
FlowSyn continuous flow reactor is making high temperature chemistry available in no time at all
06/2008
The preparation of pharmacologically important 2-amino-pyridines by direct nucleophilic displacement of unactivated 2-chloropyridine requires harsh conditions and is typically low yielding. This situation can be resolved by the use of metal catalysed cross-coupling conditions, but this necessitates more extensive purification to subsequently remove the metal catalyst. Alternatively, the direct uncatalysed preparation of 2–morpholinyl-pyridine, for example, may be straightforwardly achieved conversion under continuous throughput conditions by heating a mixture of morpholine and unactivated 2-chloropyridine to 250oC in NMP for only 20 min.
FlowSyn continuous flow reactor is making high temperature chemistry available in no time at all