Flow chemistry is an excellent method for reaction profiling and optimisation, particularly prior to scale up. High reproducibility of results coupled with short processing times allows the chemist to quickly explore a range of reaction conditions.
The FlowSyn Multiple Experiment package consists of either a Gilson FC203B or FC204 fraction collector and an enhanced FlowSyn control interface.
The FlowSyn can be programmed to perform up to 10 sequential experiments in each case varying key reaction parameters such as reaction time, temperature and stoichiometry. Once the reactions are set up, the FlowSyn will run unattended and collect the output of each experiment according to the collection protocol selected.
Reaction outputs can be either simply fractionated, or collected in 'optimise mode' whereby each reaction plug is collected into a single vial and an aliquot is directly sampled into an LCMS vial for subsequent analysis.
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